ibuprofen

[redrose]

What is in it exactly, what is it used for? and what are the side effects?

[DeAtH_sYnDrOmE]

t's like aspirin, from the family NSAID (Non Steroidal Anti Inflammatory Drug), used to treat pain, inflammation and fever. side effects include nausea, gastrointestinal ulceration/bleeding, headache, diarrhoea, dizziness, salt and fluid retention and hypertension. surely not neccessary to have these side effects. best taken after meals to avoid ulcerations and bleedings.

[redrose]

Originally Posted by DeAtH_sYnDrOmE

t's like aspirin, from the family NSAID (Non Steroidal Anti Inflammatory Drug), used to treat pain, inflammation and fever. side effects include nausea, gastrointestinal ulceration/bleeding, headache, diarrhoea, dizziness, salt and fluid retention and hypertension. surely not neccessary to have these side effects. best taken after meals to avoid ulcerations and bleedings.

I seeeee, Thanks for the info death_snydrome

now is ibuprofen only made ill pills and lyquids or are there other use's for them?

[Gardenia]

Originally Posted by redrose

What is in it exactly, what is it used for? and what are the side effects?

It is NSAID non steroidal Anti inflammatory drug which used as anti inflammatory /anti pyretic and Sedative,,
buts its main action is as sedative: reduce the pain..
its main side effect is stomach restless so u have to take it with meal or in full stomach

[Dr_XY]

Originally Posted by redrose

now is ibuprofen only made ill pills and lyquids or are there other use's for them?

# Ibuprofen is more pain and fever releifing than anti inflammatory.

# Has fewer gut side effects as compared to other
non-steroid anti-inflammatory drugs.

# Not suitable for conditions where inflammation is prominent
such as in acute gout.

# Uses of Ibuprofen :

1- Pain and inflammation in rheumatic disease
2- Pain and inflammation in Musculoskeletal disorders.
3- Fever and pain in children.
4- Mild to moderate pain in conditions like :
* Dysmenorrhea (Painful periods)
* Post operative pain
* Migraine

# Forms of Ibuprofen are :

1- Tablet



2- Syrup / Oral suspension.


3- Gel



# Ibuprofen can be pure or in a modified release formula,
or combined with codeine .

[redrose]

thanks you guys...

Its just one of my favorite medicines

[SleeplessBat]

Originally Posted by redrose

thanks you guys...

Its just one of my favorite medicines

you say it as if you use it regularly.....MEDICINE IS NOT CANDY...please use caution...it can be dangerous.





now before anyone goes off on me...i was just messing with red rose thats all




DR. XY

[Dr_XY]

Originally Posted by SleeplessBat

you say it as if you use it regularly.....MEDICINE IS NOT CANDY...please use caution...it can be dangerous.





now before anyone goes off on me...i was just messing with red rose thats all




DR. XY

[Hareega]

If you take Ibuprofen daily for a long time i can almost guarantee you'll have a big medical problem one day

I saw a lotttt of patients who had irreversible kidney damage and serious bleeding from their stomach and spent days in the ICU becuase of the use of medications like Ibuprofen (NSAIDs)

Advice: Try Tylenol or Panadol or Paracetamol first and see if it works for the pain

[Intel_InSiDe]

Originally Posted by hareega

Advice: Try Tylenol or Panadol or Paracetamol first and see if it works for the pain

i rarely use medicines but when i have headache tylenol or panadol makes nothing to me ..

advil or ibuprofen or brofen only work with me

is it that bad that i cant use it once every 2 weeks ??

[Hareega]

Originally Posted by Intel_InSiDe

i rarely use medicines but when i have headache tylenol or panadol makes nothing to me ..

advil or ibuprofen or brofen only work with me

is it that bad that i cant use it once every 2 weeks ??

sure man if you don;t have an existing kidney disease or ulcers (qor7a) in the stomach it would be ok to use it once every while and then, with food.

it's ok to have a few tablets a day (per recommendations on the pamphlet) but it's not good at all to get used to it.

[Intel_InSiDe]

Originally Posted by hareega

sure man if you don;t have an existing kidney disease or ulcers (qor7a) in the stomach it would be ok to use it once every while and then, with food.

it's ok to have a few tablets a day (per recommendations on the pamphlet) but it's not good at all to get used to it.

i got used to panadol zaman .. so now battal ye3mal ma3i ishi .. i stopped all kind of medicines since 2 years and i rarely take the painkillers such us advil>>> etc.. so i think solving the headache with a short nap or a lot of fruits / juice is much better .. and it work with me most of the times

[redrose]

Originally Posted by SleeplessBat

you say it as if you use it regularly.....MEDICINE IS NOT CANDY...please use caution...it can be dangerous.





now before anyone goes off on me...i was just messing with red rose thats all




DR. XY

i thought it was candy

hehehe .....no i dont use it much, i usually advil if i got a head ache or something.

[redrose]

Originally Posted by hareega

If you take Ibuprofen daily for a long time i can almost guarantee you'll have a big medical problem one day

I saw a lotttt of patients who had irreversible kidney damage and serious bleeding from their stomach and spent days in the ICU becuase of the use of medications like Ibuprofen (NSAIDs)

Advice: Try Tylenol or Panadol or Paracetamol first and see if it works for the pain

so ibprofen is a stronger medicine then tynlenol or the other medicines.. ?


why isnt it a perscription medicen then

[redrose]

Originally Posted by Intel_InSiDe

i rarely use medicines but when i have headache tylenol or panadol makes nothing to me ..

advil or ibuprofen or brofen only work with me

is it that bad that i cant use it once every 2 weeks ??

take as many as you wish !!!!!





j/k

[Hareega]

Originally Posted by Intel_InSiDe

i got used to panadol zaman .. so now battal ye3mal ma3i ishi .. i stopped all kind of medicines since 2 years and i rarely take the painkillers such us advil>>> etc.. so i think solving the headache with a short nap or a lot of fruits / juice is much better .. and it work with me most of the times

a7sanlak even panadol is not pefectly safe (especially if you drink a lot of alcohol i'm sure you don't lol)

[Hareega]

Originally Posted by redrose

so ibprofen is a stronger medicine then tynlenol or the other medicines.. ?


why isnt it a perscription medicen then

it's not "stronger" it's different,
morphine is much much better for pain control than any of those but it doesnt have the damaging side effects of iburpofen for example

Not all over-the-counter mecications are safe....... actually there's almost no medications without side-effects

[So What]

ibuprofen

(eye byoo' proe fen)

Actiprofen (CAN), Advil, Advil Liqui-Gels, Advil Migraine, Alti-Ibuprofen (CAN), Apo-Ibuprofen (CAN), Children's Advil, Children's Motrin, Genpril, Haltran, Infants' Motrin, Junior Strength Advil, Junior Strength Motrin, Menadol, Midol, Midol Maximum Strength Cramp, Motrin, Motrin IB, Motrin Migraine Pain, Novo-Profen (CAN), Nuprin, PediaCare Fever, Pediatric Advil Drops



Pregnancy Category B



Drug classes

Nonsteroidal anti-inflammatory drug (NSAID)

Analgesic (non-narcotic)

Propionic acid derivative



Therapeutic actions

Anti-inflammatory, analgesic, and antipyretic activities largely related to inhibition of prostaglandin synthesis; exact mechanisms of action are not known



Indications

· Relief of signs and symptoms of rheumatoid arthritis and osteoarthritis

· Relief of mild to moderate pain

· Treatment of primary dysmenorrhea

· Fever reduction



Contraindications and cautions

· Contraindicated with allergy to ibuprofen, salicylates, or other NSAIDs (more common in patients with rhinitis, asthma, chronic urticaria, nasal polyps); CV dysfunction, hypertension; peptic ulceration, GI bleeding; pregnancy; lactation.

· Use cautiously with impaired hepatic or renal function.



Available forms

Tablets--100, 200, 400, 600, 800 mg; chewable tablets--50, 100 mg; capsules--200 mg; suspension--100 mg/2.5 mL, 100 mg/5 mL; oral drops--40 mg/mL


Dosages

ADULTS

Do not exceed 3,200 mg/day.

· Mild to moderate pain: 400 mg q 4–6 hr PO.

· Osteoarthritis/rheumatoid arthritis: 1,200–3,200 mg/day PO (300 mg qid or 400, 600, 800 mg tid or qid; individualize dosage. Therapeutic response may occur in a few days, but often takes 2 wk).

· Primary dysmenorrhea: 400 mg q 4 hr PO.

· OTC use: 200–400 mg q 4–6 hr PO while symptoms persist; do not exceed 1,200 mg/day. Do not take for more than 10 days for pain or 3 days for fever, unless so directed by health care provider.

PEDIATRIC PATIENTS

· Juvenile arthritis: 30–40 mg/kg/day PO in three to four divided doses; 20 mg/kg/day for milder disease.

· Fever (6 mo–12 yr): 5–10 mg/kg PO q 6–8 hr; do not exceed 40 mg/kg/day.



Pharmacokinetics

Route
Onset
Peak
Duration

Oral
30 min
1–2 hr
4–6 hr




Metabolism: Hepatic; T1/2: 1.8–2.5 hr

Distribution: Crosses placenta; may enter breast milk

Excretion: Urine



Adverse effects

NSAIDs

· CNS: Headache, dizziness, somnolence, insomnia, fatigue, tiredness, dizziness, tinnitus, ophthalmologic effects

· Dermatologic: Rash, pruritus, sweating, dry mucous membranes, stomatitis

· GI: Nausea, dyspepsia, GI pain, diarrhea, vomiting, constipation, flatulence, GI bleeding

· GU: Dysuria, renal impairment, menorrhagia

· Hematologic: Bleeding, platelet inhibition with higher doses, neutropenia, eosinophilia, leukopenia, pancytopenia, thrombocytopenia, agranulocytosis, granulocytopenia, aplastic anemia, decreased Hgb or Hct, bone marrow depression

· Respiratory: Dyspnea, hemoptysis, pharyngitis, bronchospasm, rhinitis

· Other: Peripheral edema, anaphylactoid reactions to anaphylactic shock



Interactions

Drug-drug

· Increased toxic effects of lithium with ibuprofen

· Decreased diuretic effect with loop diuretics: bumetanide, furosemide, ethacrynic acid

· Potential decrease in antihypertensive effect of beta-adrenergic blocking agents



Nursing considerations

Assessment

· History: Allergy to ibuprofen, salicylates or other NSAIDs; CV dysfunction, hypertension; peptic ulceration, GI bleeding; impaired hepatic or renal function; pregnancy; lactation

· Physical: Skin color, lesions; T; orientation, reflexes, ophthalmologic evaluation, audiometric evaluation, peripheral sensation; P, BP, edema; R, adventitious sounds; liver evaluation, bowel sounds; CBC, clotting times, urinalysis, renal and liver function tests, serum electrolytes, stool guaiac



Interventions

· Administer drug with food or after meals if GI upset occurs.

· Arrange for periodic ophthalmologic examination during long-term therapy.

· Discontinue drug if eye changes, symptoms of liver dysfunction, renal impairment occur.

· Institute emergency procedures if overdose occurs: gastric lavage, induction of emesis, supportive therapy.



Teaching points

· Use drug only as suggested; avoid overdose. Take the drug with food or after meals if GI upset occurs. Do not exceed the prescribed dosage.

· These side effects may occur: nausea, GI upset, dyspepsia (take drug with food); diarrhea or constipation; drowsiness, dizziness, vertigo, insomnia (use caution when driving or operating dangerous machinery).

· Avoid OTC drugs. Many of these drugs contain similar medications, and serious overdosage can occur.

· Report sore throat, fever, rash, itching, weight gain, swelling in ankles or fingers, changes in vision, black or tarry stools.



Adverse effects in Italic are most common; those in Bold are life-threatening.

[redrose]

Originally Posted by So What

ibuprofen

(eye byoo' proe fen)

Actiprofen (CAN), Advil, Advil Liqui-Gels, Advil Migraine, Alti-Ibuprofen (CAN), Apo-Ibuprofen (CAN), Children's Advil, Children's Motrin, Genpril, Haltran, Infants' Motrin, Junior Strength Advil, Junior Strength Motrin, Menadol, Midol, Midol Maximum Strength Cramp, Motrin, Motrin IB, Motrin Migraine Pain, Novo-Profen (CAN), Nuprin, PediaCare Fever, Pediatric Advil Drops



Pregnancy Category B



Drug classes

Nonsteroidal anti-inflammatory drug (NSAID)

Analgesic (non-narcotic)

Propionic acid derivative



Therapeutic actions

Anti-inflammatory, analgesic, and antipyretic activities largely related to inhibition of prostaglandin synthesis; exact mechanisms of action are not known



Indications

· Relief of signs and symptoms of rheumatoid arthritis and osteoarthritis

· Relief of mild to moderate pain

· Treatment of primary dysmenorrhea

· Fever reduction



Contraindications and cautions

· Contraindicated with allergy to ibuprofen, salicylates, or other NSAIDs (more common in patients with rhinitis, asthma, chronic urticaria, nasal polyps); CV dysfunction, hypertension; peptic ulceration, GI bleeding; pregnancy; lactation.

· Use cautiously with impaired hepatic or renal function.



Available forms

Tablets--100, 200, 400, 600, 800 mg; chewable tablets--50, 100 mg; capsules--200 mg; suspension--100 mg/2.5 mL, 100 mg/5 mL; oral drops--40 mg/mL


Dosages

ADULTS

Do not exceed 3,200 mg/day.

· Mild to moderate pain: 400 mg q 4–6 hr PO.

· Osteoarthritis/rheumatoid arthritis: 1,200–3,200 mg/day PO (300 mg qid or 400, 600, 800 mg tid or qid; individualize dosage. Therapeutic response may occur in a few days, but often takes 2 wk).

· Primary dysmenorrhea: 400 mg q 4 hr PO.

· OTC use: 200–400 mg q 4–6 hr PO while symptoms persist; do not exceed 1,200 mg/day. Do not take for more than 10 days for pain or 3 days for fever, unless so directed by health care provider.

PEDIATRIC PATIENTS

· Juvenile arthritis: 30–40 mg/kg/day PO in three to four divided doses; 20 mg/kg/day for milder disease.

· Fever (6 mo–12 yr): 5–10 mg/kg PO q 6–8 hr; do not exceed 40 mg/kg/day.



Pharmacokinetics

Route
Onset
Peak
Duration

Oral
30 min
1–2 hr
4–6 hr




Metabolism: Hepatic; T1/2: 1.8–2.5 hr

Distribution: Crosses placenta; may enter breast milk

Excretion: Urine



Adverse effects

NSAIDs

· CNS: Headache, dizziness, somnolence, insomnia, fatigue, tiredness, dizziness, tinnitus, ophthalmologic effects

· Dermatologic: Rash, pruritus, sweating, dry mucous membranes, stomatitis

· GI: Nausea, dyspepsia, GI pain, diarrhea, vomiting, constipation, flatulence, GI bleeding

· GU: Dysuria, renal impairment, menorrhagia

· Hematologic: Bleeding, platelet inhibition with higher doses, neutropenia, eosinophilia, leukopenia, pancytopenia, thrombocytopenia, agranulocytosis, granulocytopenia, aplastic anemia, decreased Hgb or Hct, bone marrow depression

· Respiratory: Dyspnea, hemoptysis, pharyngitis, bronchospasm, rhinitis

· Other: Peripheral edema, anaphylactoid reactions to anaphylactic shock



Interactions

Drug-drug

· Increased toxic effects of lithium with ibuprofen

· Decreased diuretic effect with loop diuretics: bumetanide, furosemide, ethacrynic acid

· Potential decrease in antihypertensive effect of beta-adrenergic blocking agents



Nursing considerations

Assessment

· History: Allergy to ibuprofen, salicylates or other NSAIDs; CV dysfunction, hypertension; peptic ulceration, GI bleeding; impaired hepatic or renal function; pregnancy; lactation

· Physical: Skin color, lesions; T; orientation, reflexes, ophthalmologic evaluation, audiometric evaluation, peripheral sensation; P, BP, edema; R, adventitious sounds; liver evaluation, bowel sounds; CBC, clotting times, urinalysis, renal and liver function tests, serum electrolytes, stool guaiac



Interventions

· Administer drug with food or after meals if GI upset occurs.

· Arrange for periodic ophthalmologic examination during long-term therapy.

· Discontinue drug if eye changes, symptoms of liver dysfunction, renal impairment occur.

· Institute emergency procedures if overdose occurs: gastric lavage, induction of emesis, supportive therapy.



Teaching points

· Use drug only as suggested; avoid overdose. Take the drug with food or after meals if GI upset occurs. Do not exceed the prescribed dosage.

· These side effects may occur: nausea, GI upset, dyspepsia (take drug with food); diarrhea or constipation; drowsiness, dizziness, vertigo, insomnia (use caution when driving or operating dangerous machinery).

· Avoid OTC drugs. Many of these drugs contain similar medications, and serious overdosage can occur.

· Report sore throat, fever, rash, itching, weight gain, swelling in ankles or fingers, changes in vision, black or tarry stools.



Adverse effects in Italic are most common; those in Bold are life-threatening.

WOW.. thanks so what